Wuhan Fine Biotech Co., Ltd.'s TRBP antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, Precipitation, ELISA, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, and Western Blot. The TRBP antibody was generated using TARBP2, and TARBP2 subunit of RISC loading complex as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
TARBP2 is a component of the RISC loading complex(RLC), also known as the micro-RNA(miRNA) loading complex(miRLC). Within the complex, TARBP2 and DICER1 are required to process precursor miRNAs(pre-miRNA) to mature miRNA and then load them onto EIF2C2/AGO2. It may has a role in the production of short interfering RNAs(siRNAs) from double-stranded RNA(dsRNA) by DICER1. Otherwise, it binds to the HIV-1 TAR RNA that is located in the long terminal repeat(LTR) of HIV-1, and stimulates translation of TAR-containing RNAs